Open AccessMicroparticles: Reliable Markers of Thrombosis
Author(s) -
Shelly Chopra
Publication year - 2012
Publication title -
meducator
Language(s) - English
Resource type - Journals
eISSN - 1929-4239
pISSN - 1929-4220
DOI - 10.15173/m.v1i20.787
Subject(s) - extracellular vesicles , thrombosis , pathological , apoptosis , microbiology and biotechnology , bioinformatics , medicine , biology , immunology , pathology , biochemistry
Microparticles are vesicles that bud off cells in response to extracellular stimulation or apoptosis. They play an important role in the regulation of physiological and pathological pathways such as clot formation and the progression of thrombotic disease by influencing the expression of critical proteins and cofactors. The following Critical Review evaluates research findings on the potential significance of microparticles as indicators of thrombotic risk.