Open AccessGlucose and Lipid Abnormalities in Newly Diagnosed Acromegalic Patients
Author(s) -
Mihaela Vlad,
Daniela Amzăr,
Diana Bănică,
Ioana Golu,
Melania Balaș,
Adrian Vlad,
Romulus Timar,
Ioana Zosin
Publication year - 2015
Publication title -
romanian journal of diabetes nutrition and metabolic diseases
Language(s) - English
Resource type - Journals
eISSN - 2284-6417
pISSN - 2068-8245
DOI - 10.1515/rjdnmd-2015-0006
Subject(s) - acromegaly , medicine , diabetes mellitus , lipid metabolism , cholesterol , endocrinology , carbohydrate metabolism , lipid profile , gastroenterology , hormone , growth hormone
Background and Aims. Acromegaly is frequently associated with abnormalities of glucose and lipid metabolism. The aim of our study was to analyze the prevalence of glucose and lipid metabolism abnormalities in newly diagnosed acromegaly patients. Material and Methods. This retrospective study included 14 patients (F/M=10/4), mean age 49.5 ± 10.6 years, registered with acromegaly between January and December 2013. In all the cases the values of blood glucose (fasting and during the oral glucose tolerance test), total cholesterol and triglycerides were analyzed. The glucose disorders were classified according to the current criteria of the American Diabetes Association. Regarding the lipid metabolism, the cases were classified as having normal cholesterol, normal triglycerides, high cholesterol and high triglycerides. Results. A number of 7 patients (50%) presented abnormalities of glucose metabolism. The prevalence of diabetes mellitus (14.3%) was lower compared to that reported by other studies (15.5%- 56%). Abnormalities of lipid metabolism were present in 8 patients (57.2%): high cholesterol was detected in 2 cases and 6 cases presented increased values for both cholesterol and triglycerides. Only 4/14 cases (28.6%) presented normal values for all glucose and lipid metabolisms parameters. Conclusions. Abnormalities of glucose and lipid metabolisms are very common in acromegalic patients