Open AccessHigh‐intensity training in normobaric hypoxia enhances exercise performance and aerobic capacity in Thoroughbred horses: A randomized crossover study
Author(s) -
Mukai Kazutaka,
Ohmura Hajime,
Matsui Akira,
Aida Hiroko,
Takahashi Toshiyuki,
Jones James H.
Publication year - 2020
Publication title -
physiological reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 39
ISSN - 2051-817X
DOI - 10.14814/phy2.14442
Subject(s) - crossover study , hypoxia (environmental) , medicine , vo2 max , treadmill , aerobic exercise , endurance training , cardiac output , stroke volume , heart rate , time trial , aerobic capacity , cardiology , hemodynamics , zoology , endocrinology , oxygen , blood pressure , chemistry , biology , alternative medicine , organic chemistry , pathology , placebo
We examined the effects of high‐intensity training in normobaric hypoxia on aerobic capacity and exercise performance in horses and the individual response to normoxic and hypoxic training. Eight untrained horses were studied in a randomized, crossover design after training in hypoxia (HYP; 15.0% inspired O 2 ) or normoxia (NOR; 20.9% inspired O 2 ) 3 days/week for 4 weeks separated by a 4‐month washout period. Before and after each training period, incremental treadmill exercise tests were performed in normoxia. Each training session consisted of 1 min cantering at 7 m/s and 2 min galloping at the speed determined to elicit maximal oxygen consumption ( V ˙ O 2 max) in normoxia. Hypoxia increased significantly more than NOR in run time to exhaustion (HYP, +28.4%; NOR, +10.4%, p = .001), V ˙ O 2 max (HYP, +12.1%; NOR, +2.6%, p = .042), cardiac output ( Q ˙ ; HYP, +11.3%; NOR, −1.7%, p = .019), and stroke volume ( SV ) at exhaustion (HYP, +5.4%; NOR, −5.5%, p = .035) after training. No significant correlations were observed between NOR and HYP for individual changes after training in run time ( p = .21), V ˙ O 2 max ( p = .99), Q ˙ ( p = .19), and SV ( p = .46) at exhaustion. Arterial O 2 saturation during exercise in HYP was positively correlated with the changes in run time ( r = .85, p = .0073), Q ˙ ( r = .72, p = .043) and SV ( r = .77, p = .026) of HYP after training, whereas there were no correlations between these parameters in NOR. These results suggest that high‐intensity training in normobaric hypoxia improved exercise performance and aerobic capacity of horses to a greater extent than the same training protocol in normoxia, and the severity of hypoxemia during hypoxic exercise might be too stressful for poor responders to hypoxic training.