Open AccessCardiovascular and cerebral hemodynamics during exercise and recovery in obese individuals as a function of their fitness status
Author(s) -
Gayda Mathieu,
Lapierre Gabriel,
Dupuy Olivier,
Fraser Sarah,
Bherer Louis,
Juneau Martin,
Gremeaux Vincent,
Nigam Anil
Publication year - 2017
Publication title -
physiological reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 39
ISSN - 2051-817X
DOI - 10.14814/phy2.13321
Subject(s) - impedance cardiography , medicine , hemodynamics , cardiology , aerobic exercise , blood pressure , heart rate , cardiac output , cerebral perfusion pressure , cardiac index , cardiac function curve , perfusion , heart failure , stroke volume
The aim of this study was to compare cardiovascular hemodynamics and cerebral oxygenation/perfusion ( COP ) during and after maximal incremental exercise in obese individuals according to their aerobic fitness versus age‐matched healthy controls ( AMHC ). Fifty‐four middle–aged obese ( OB ) and 16 AMHC were recruited. Maximal cardiopulmonary function (gas exchange analysis), cardiac hemodynamics (impedance cardiography), and left frontal COP (near‐infrared spectroscopy: NIRS ) were measured continuously during a maximal incremental ergocycle test. During recovery, reoxygenation/perfusion rate ( ROPR : oxyhemoglobin: ΔO 2 Hb, deoxyhemoglobin: Δ HH b and total hemoglobin: ΔtHb; with NIRS ) was also measured. Obese participants ( OB , n = 54) were divided into two groups according to the medianV ˙ O 2peak: the low‐fit obese ( LF ‐ OB , n = 27) and the high‐fit obese ( HF ‐ OB , n = 27). During exercise, end tidal pressure of CO 2 ( PETCO 2 ), and COP (ΔO 2 Hb, Δ HH b and ΔtHb) did not differ between groups ( OB , LF ‐ OB , HF ‐ OB , AMHC ). During recovery, PETCO 2 and ROPR (ΔO 2 Hb, Δ HH b and ΔtHb) were similar between the groups ( OB , LF ‐ OB , HF ‐ OB , AMHC ). During exercise and recovery, cardiac index was lower ( P < 0.05) in LF ‐ OB versus the other two groups ( HF ‐ OB , AMHC ). As well, systolic blood pressure was higher during exercise in the OB , LF ‐ OB and HF ‐ OB groups versus AMHC ( P < 0.05). When compared to AMHC , obese individuals ( OB , LF ‐ OB , HF ‐ OB ) have a similar cerebral vasoreactivity by CO 2 and cerebral hemodynamics during exercise and recovery, but a higher systolic blood pressure during exercise. Higher fitness in obese subjects ( HF ‐ OB ) seems to preserve their cardiopulmonary and cardiac function during exercise and recovery.