Open AccessImpact of type 2 diabetes on cardiorespiratory function and exercise performance
Author(s) -
Caron Joanie,
duManoir Gregory R.,
Labrecque Lawrence,
Chouinard Audrey,
Ferland Annie,
Poirier Paul,
Legault Sylvie,
Brassard Patrice
Publication year - 2017
Publication title -
physiological reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 39
ISSN - 2051-817X
DOI - 10.14814/phy2.13145
Subject(s) - cardiorespiratory fitness , medicine , ventilatory threshold , type 2 diabetes , vo2 max , cardiology , diabetes mellitus , anthropometry , body mass index , heart rate , blood pressure , physical therapy , endocrinology
The aim of this study was to examine the impact of well‐controlled uncomplicated type 2 diabetes (T2D) on exercise performance. Ten obese sedentary men with T2D and nine control participants without diabetes matched for age, sex, and body mass index were recruited. Anthropometric characteristics, blood samples, resting cardiac, and pulmonary functions and maximal oxygen uptake ( V O 2max ) and ventilatory threshold were measured on a first visit. On the four subsequent visits, participants (diabetics: n = 6; controls: n = 7) performed step transitions (6 min) of moderate‐intensity exercise on an upright cycle ergometer from unloaded pedaling to 80% of ventilatory threshold. V O 2 ( τV O 2 ) and HR ( τ HR ) kinetics were characterized with a mono‐exponential model. V O 2max (27.0 ± 3.4 vs. 26.7 ± 5.0 mL kg −1 min −1 ; P = 0.85), τV O 2 (43 ± 6 vs. 43 ± 10 sec; P = 0.73), and τ HR (42 ± 17 vs. 43 ± 13 sec; P = 0.94) were similar between diabetics and controls respectively. The remaining variables were also similar between groups, with the exception of lower maximal systolic blood pressure in diabetics ( P = 0.047). These results suggest that well‐controlled T2D is not associated with a reduction in V O 2max or slower τV O 2 and τ HR .