Open AccessThere and back again: insulin, EN aC, and the cortical collecting duct
Author(s) -
Pao Alan C.
Publication year - 2016
Publication title -
physiological reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 39
ISSN - 2051-817X
DOI - 10.14814/phy2.12809
Subject(s) - insulin , epithelial sodium channel , medicine , computer science , endocrinology , bioinformatics , chemistry , biology , sodium , organic chemistry
Cell culture models suggest mechanisms by which insulin stimulates ENaC in the cortical collecting duct. These mechanisms still need to be tested for physiological significance in animal models of insulin resistance.