Open AccessMaximal exercise does not increase ventilation heterogeneity in healthy trained adults
Author(s) -
Wrobel Jeremy P.,
Ellis Matthew J.,
Kee Kirk,
StuartAndrews Christopher R.,
Thompson Bruce R.
Publication year - 2016
Publication title -
physiological reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 39
ISSN - 2051-817X
DOI - 10.14814/phy2.12747
Subject(s) - ventilation (architecture) , medicine , cardiology , hypoxemia , respiratory minute volume , physical therapy , respiratory system , engineering , mechanical engineering
Abstract The effect of exercise on ventilation heterogeneity has not been investigated. We hypothesized that a maximal exercise bout would increase ventilation heterogeneity. We also hypothesized that increased ventilation heterogeneity would be associated with exercise‐induced arterial hypoxemia ( EIAH ). Healthy trained adult males were prospectively assessed for ventilation heterogeneity using lung clearance index ( LCI ), S cond , and S acin at baseline, postexercise and at recovery, using the multiple breath nitrogen washout technique. The maximal exercise bout consisted of a maximal, incremental cardiopulmonary exercise test at 25 watt increments. Eighteen subjects were recruited with mean ± SD age of 35 ± 9 years. There were no significant changes in LCI , S cond , or S acin following exercise or at recovery. While there was an overall reduction in SpO 2 with exercise (99.3 ± 1 to 93.7 ± 3%, P < 0.0001), the reduction in SpO 2 was not associated with changes in LCI , S cond or S acin . Ventilation heterogeneity is not increased following a maximal exercise bout in healthy trained adults. Furthermore, EIAH is not associated with changes in ventilation heterogeneity in healthy trained adults.