Open AccessState-of-the-Art Treatments for Sarcoidosis
Author(s) -
Ilias Papanikolaou,
Emmanouil Antonakis,
Aggeliki Pandi
Publication year - 2022
Publication title -
methodist debakey cardiovascular journal
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.552
H-Index - 23
eISSN - 1947-6094
pISSN - 1947-6108
DOI - 10.14797/mdcvj.1068
Subject(s) - sarcoidosis , medicine , granulomatous disease , disease , fibrosis , systemic disease , intensive care medicine , dermatology , pathology
Sarcoidosis is a heterogeneous disease with various treatment indications. Although it affects mainly the lungs, sarcoidosis can affect every organ, especially when the disease course is chronic and protracted. Regular patient follow-up is recommended for early recognition of active, ongoing organ-specific granulomatous inflammation to avoid progression to irreversible fibrosis. In this review, we elaborate on treatment indications and various anti-sarcoidosis regimens proven useful in clinical trials. We also review specialized treatment of specific disease manifestations, with a focus on cardiac sarcoidosis. We also report on treatment for special conditions such as fatigue and small fiber neuropathy. Treatment for sarcoidosis is an emerging landscape, with new data complementing the existing knowledge.