Open AccessBRASH Syndrome with Hyperkalemia: An Under-Recognized Clinical Condition
Author(s) -
Abdul Wahab Arif,
Muhammad Shahzeb Khan,
Abdallah Masri,
) Benjamin,
Muhammad Ayub,
Rami Doukky
Publication year - 2020
Publication title -
methodist debakey cardiovascular journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.552
H-Index - 23
eISSN - 1947-6094
pISSN - 1947-6108
DOI - 10.14797/mdcj-16-3-241
Subject(s) - medicine , hyperkalemia , bradycardia , renal function , cardiology , shock (circulatory) , intensive care medicine , heart rate , blood pressure
BRASH syndrome is characterized by bradycardia, renal failure, use of an atrioventricular nodal blocker (AVNB), shock, and hyperkalemia. These symptoms represent an ongoing vicious cycle in a patient with a low glomerular filtration rate taking an AVNB. Decreased clearance of the medication and hyperkalemia associated with renal failure synergize to cause bradycardia and hypoperfusion. This reaction causes renal function to worsen, thereby perpetuating the cycle of BRASH syndrome.