Ameliorating Effects of Adalimumab on Rabbits with Experimental Cerebral Vasospasm After Subarachnoid Hemorrhage | Zendy

Gökhan Toğuşlu | Zendy

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Ameliorating Effects of Adalimumab on Rabbits with Experimental Cerebral Vasospasm After Subarachnoid Hemorrhage

Author(s) -

Gökhan Toğuşlu

Publication year - 2020

Publication title -

turkish journal of trauma and emergency surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.28

H-Index - 22

ISSN - 1306-696X

DOI - 10.14744/tjtes.2019.52504

Subject(s) - subarachnoid hemorrhage , medicine , cerebral vasospasm , vasospasm , anesthesia

Adalimumab (ADA), which is a new-generation recombinant human monoclonal antibody for tumor necrosis factor α (TNFα), has strong anti-inflammatory effects. The role of enhanced inflammation is well established for the development and progression of cerebral vasospasm. Investigated in the present study is the probable ameliorating and neuroprotective effects of ADA in rabbits using a cerebral vasospasm model with biochemical and histopathological methods.

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