Open AccessUndifferentiated Carcinoma of the Pancreas – a Case Report
Author(s) -
Barbora Judita Kasperová,
Silvia Jurišová,
Ján Macúch,
Miroslava Bumberová,
Pavol Janega,
Jozef Dolinský,
Michal Mego
Publication year - 2018
Publication title -
klinická onkologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.204
H-Index - 13
eISSN - 1802-5307
pISSN - 0862-495X
DOI - 10.14735/amko2018453
Subject(s) - medicine , gemcitabine , pancreas , carcinosarcoma , pancreatic cancer , chemotherapy , adenocarcinoma , folfirinox , oncology , carcinoma , pathology , cancer , radiation therapy , metastasis , irinotecan , colorectal cancer
Undifferentiated carcinoma of pancreas (pancreatic cancer - PC) is a rare subtype of malignant PC. It was thought to be a sarcoma of the pancreas due to its typical morphological pattern. There are three histomorphological variants: anaplastic, sarcomatoid, and carcinosarcoma. There is also a separate category: undifferentiated pancreatic carcinoma with osteoclast-like giant cells. In contrast to ductal adenocarcinoma of the pancreas, undifferentiated carcinoma of pancreas is characterized by more aggressive behavior, other predilection localization of tumor and different predilection for localization of tumor and metastasis, a larger primary tumor, and different symptomatology at the time of diagnosis.