Down-regulation of TSGA10, AURKC, OIP5 and AKAP4 genes by Lactobacillus rhamnosus GG and Lactobacillus crispatus SJ-3C-US supernatants in HeLa cell line | Zendy

Zahra Nouri | Zendy; Nadia Neyazi | Zendy; Mohammad Hossein Modarressi | Zendy; Fatemeh Karami | Zendy; Atieh AbedinDo | Zendy; Zahra TaherianEsfahani | Zendy; Soudeh GhafouriFard | Zendy; Elahe Motevaseli | Zendy

Open Access

Down-regulation of TSGA10, AURKC, OIP5 and AKAP4 genes by Lactobacillus rhamnosus GG and Lactobacillus crispatus SJ-3C-US supernatants in HeLa cell line

Author(s) -

Zahra Nouri,

Nadia Neyazi,

Mohammad Hossein Modarressi,

Fatemeh Karami,

Atieh AbedinDo,

Zahra TaherianEsfahani,

Soudeh GhafouriFard,

Elahe Motevaseli

Publication year - 2018

Publication title -

klinicka onkologie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.204

H-Index - 13

eISSN - 1802-5307

pISSN - 0862-495X

DOI - 10.14735/amko2018429

Subject(s) - hela , lactobacillus rhamnosus , biology , lactobacillus crispatus , cancer , cell culture , cancer research , lactobacillus , cancer cell , epigenetics , microbiology and biotechnology , gene , genetics , bacteria

Cancer testis antigens (CTAs) are considered cancer bio-markers due to their highly specific expression pattern in human malignancies and near absence from normal somatic tissues. Their specific expression has made them potential targets for early dia-gnosis, assessment of patients prognosis and treatment of cancer in recent years. Lactobacilli are a group of probio-tics with anti-cancer, immunomodulatory and other beneficial features. These bacteria have been shown to alter expression of several cancer-related genes.

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