Open AccessInfiltration of Prostate Cancer by CD204+ and CD3+ Cells Correlates with ERG Expression and TMPRSS2-ERG Gene Fusion
Author(s) -
Alena Burdová,
P Rulisek,
Jan Bouchal,
Milan Král,
V. Študent,
Z Kolár
Publication year - 2018
Publication title -
klinická onkologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.204
H-Index - 13
eISSN - 1802-5307
pISSN - 0862-495X
DOI - 10.14735/amko2018421
Subject(s) - erg , tmprss2 , prostate , hyperplasia , infiltration (hvac) , fusion gene , prostate cancer , pathology , biology , medicine , cancer , gene , retina , biochemistry , physics , disease , covid-19 , neuroscience , infectious disease (medical specialty) , thermodynamics
The aim of the study was to detect CD204 + and CD3 + cells in the infiltrate of benign prostatic hyperplasia, prostatic intraepithelial neoplasia and prostatic cancer in prostate specimens after radical prostatectomy. Another goal was to determine correlation of the intensity of the infiltration with ERG oncoprotein expression as well as with the presence of activat-ing translocation TMPRSS2-ERG.