Infiltration of Prostate Cancer by CD204+ and CD3+ Cells Correlates with ERG Expression and TMPRSS2-ERG Gene Fusion | Zendy

Alena Burdová | Zendy; Patrik Rulíšek | Zendy; Jan Bouchal | Zendy; Milan Král | Zendy; V. Študent | Zendy; Zdeněk Kolář | Zendy

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Infiltration of Prostate Cancer by CD204+ and CD3+ Cells Correlates with ERG Expression and TMPRSS2-ERG Gene Fusion

Author(s) -

Alena Burdová,

Patrik Rulíšek,

Jan Bouchal,

Milan Král,

V. Študent,

Zdeněk Kolář

Publication year - 2018

Publication title -

klinicka onkologie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.204

H-Index - 13

eISSN - 1802-5307

pISSN - 0862-495X

DOI - 10.14735/amko2018421

Subject(s) - erg , tmprss2 , prostate , hyperplasia , infiltration (hvac) , fusion gene , prostate cancer , pathology , biology , medicine , cancer , gene , retina , biochemistry , physics , disease , covid-19 , neuroscience , infectious disease (medical specialty) , thermodynamics

The aim of the study was to detect CD204 + and CD3 + cells in the infiltrate of benign prostatic hyperplasia, prostatic intraepithelial neoplasia and prostatic cancer in prostate specimens after radical prostatectomy. Another goal was to determine correlation of the intensity of the infiltration with ERG oncoprotein expression as well as with the presence of activat-ing translocation TMPRSS2-ERG.

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