Open AccessMonoclonal Gammopathy of Undetermined Significance (MGUS)
Author(s) -
Viera Sandecká,
Luděk Pour,
Zdeněk Adam,
Marta Krejčí,
Martin Štork,
Sabina Ševčı́ková,
Zdeněk Král
Publication year - 2018
Publication title -
klinická onkologie
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.204
H-Index - 13
eISSN - 1802-5307
pISSN - 0862-495X
DOI - 10.14735/amko2018270
Subject(s) - monoclonal gammopathy of undetermined significance , multiple myeloma , medicine , macroglobulinemia , bone marrow , lymphoproliferative disorders , immunoglobulin light chain , serum protein electrophoresis , waldenstrom macroglobulinemia , pathology , gammopathy , asymptomatic , monoclonal , hematology , immunology , gastroenterology , lymphoma , antibody , monoclonal antibody
Monoclonal gammopathy of undetermined significance (MGUS) is one of the most prevalent premalignant conditions associated with a risk of malignant transformation to multiple myeloma (MM) or other forms of lymphoproliferative disorders with risk of progression of approximately 1% per year. IgG and IgA MGUS are precursor conditions of multiple myeloma (MM), whereas light-chain MGUS is a precursor condition of light chain MM. IgM MGUS is a precursor condition of Waldenström macroglobulinemia (MW) or other lymphoproliferative diseases.