Open AccessGenetic biomarkers: Potential roles in cancer diagnosis
Author(s) -
Rozhgar A. Khailany,
Sherwan Ahmed Aziz,
S. Najjar,
Muhammad Safdar,
Mehmet Özaslan
Publication year - 2020
Publication title -
cellular and molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.371
H-Index - 71
eISSN - 1165-158X
pISSN - 0145-5680
DOI - 10.14715/cmb/2020.66.3.1
Subject(s) - cancer , disease , epigenetics , medicine , bioinformatics , epidemiology , diagnostic biomarker , intensive care medicine , computational biology , biology , pathology , genetics , gene
Biomarkers are indicators of pathogenic processes, typical biological processes, or pharmacological reactions to a therapy. It has several potential usages in cancer; differential diagnosis, prognosis, risk assessment, therapeutic response, and monitoring of disease progression. Recently, advances in oncomarkers raised significant opportunities for enhancing management of cancer. Chromosomal aberration, molecular impairment and epigenetic alteration might be applied to diagnose and prognose cancer and its epidemiology. Some oncomarkers are specific and highly sensitive for detection. An oncomarker might be used to see how the body reacts to an intervention or a situation. The present study represents a short review about various genetic oncomarkers with diagnostic and prognostic values.