Open AccessFingerroot (Boesenbergia pandurata) : A Prospective Anticancer Therapy
Author(s) -
Marsya Yonurrachma,
Hilyatul Fadliyah,
Edy Meiyanto
Publication year - 2018
Publication title -
iscc (indonesian journal of cancer chemoprevention)
Language(s) - English
Resource type - Journals
eISSN - 2355-8989
pISSN - 2088-0197
DOI - 10.14499/indonesianjcanchemoprev9iss2pp102-109
Subject(s) - traditional medicine , phytochemical , rhizome , poly adp ribose polymerase , pharmacology , medicine , chemistry , polymerase , biochemistry , dna
Beside as a spice in Indonesian cooking, Fingerroot (Boesenbergia pandurata) regularly is used as a mixture of herbal medicine. Scientifically, the phytochemical content of the fingerroot rhizome showed some therapeutical effects such as antibacterial, anti-inflammatory, anti or pro-oxidant, and also anticancer. In this article, we summarize some studies especially about anticancer activity of fingerroot and its constituent coumpound. We found that fingerroot is capable of inhibiting various pathways of cell physiology processes. One potential pathway to be inhibited by fingerroot is Poly (ADP-ribose) polymerase (PARP) which has role in apoptotic induction. In the future, it is necessary to purify the extract to obtain maximum efficacy and also formulation studies of fingerroot will be interesting to do to.