Open AccessAsymptomatic Hyperuricemia
Author(s) -
Hosoya Tatsuo,
Nishio Shinichiro
Publication year - 2016
Publication title -
journal of general and family medicine
Language(s) - English
Resource type - Journals
ISSN - 2189-7948
DOI - 10.14442/jgfm.17.1_71
Subject(s) - hyperuricemia , medicine , asymptomatic , gout , disease , stroke (engine) , kidney disease , clinical trial , uric acid , intensive care medicine , febuxostat , cardiology , mechanical engineering , engineering
According to recent study, hyperuricemia is not only a basic pathology of gout, but has been found that it is intimately related to the development and progress of hypertension, chronic renal disease (CKD), cardiovascular disease, and stroke. This means that hypertension, CKD and cardiovascular disease are caused by the direct effect (pro‐oxidant effect) of urate without going through urate crystal deposition. If the above issues can be indicated as clear evidence by treatment of interventional clinical trials, it can be thought that the treatment strategy for hyperuricemia to prevent organ damage will see substantial progress.