Open AccessCronkhite‐Canada Syndrome with Complete Remission after Four Months of Prednisolone Therapy and Polypectomy
Author(s) -
Namikawa Hiroki,
Takemoto Yasuhiko,
Kamata Noriko,
Yashiro Masakazu,
Hirohashi Kazuhiro,
Shuto Taichi
Publication year - 2015
Publication title -
journal of general and family medicine
Language(s) - English
Resource type - Journals
ISSN - 2189-7948
DOI - 10.14442/jgfm.16.4_297
Subject(s) - medicine , prednisolone , polypectomy , etiology , gastroenterology , biopsy , surgery , colonoscopy , colorectal cancer , cancer
The etiology of and optimal treatments for Cronkhite‐Canada syndrome (CCS) are still undetermined. Fewer than 5% of CCS patients experience complete remission and 15% of CCS patients develop malignancies. Here, we present a case of CCS involving autoimmune disorders, in which rapid diagnosis, rapid commencement of therapy, and complete remission were achieved after 4 months of prednisolone therapy and polypectomy, although biopsy specimens from all residual colonic polyps revealed adenocarcinoma in one polyp 4 months after prednisolone therapy. It is important to identify gastrointestinal or colonic polyps harboring malignant changes and to examine the involvement of autoimmune mechanisms for better outcomes in CCS patients.