Open AccessPolycystic Kidney Complicated by Cholangiocellular Carcinoma Presenting as Fever of Unknown Origin
Author(s) -
Ikeda Nobuhiro,
Naito Toshio,
Isonuma Hiroshi,
Dambara Takashi,
Hayashida Yasuo
Publication year - 2005
Publication title -
general medicine
Language(s) - English
Resource type - Journals
eISSN - 1883-6011
pISSN - 1346-0072
DOI - 10.14442/general2000.6.23
Subject(s) - differential diagnosis , malignancy , medicine , fever of unknown origin , autopsy , pathology , adenocarcinoma , carcinoma , hepatocellular carcinoma , polycystic kidney , biopsy , radiology , polycystic kidney disease , kidney , cyst , cancer
We report the case of a 59‐year‐old man who presented with classical‐type fever of unknown origin (FUO) during observation of hypertension and polycystic kidney. The presence of malignancy was suspected based on elevation of tumor marker levels. We examined the patient carefully and attempted diagnostic imaging, but definitive diagnosis was difficult due to the presence of multiple hepatic cysts. Hepatic biopsy detected adenocarcinoma, but identifying whether lesions were primary cholangiocellular carcinoma or metastases was difficult, and we were ultimately unable to diagnose the tumors as cholangiocellular carcinoma until autopsy. Polycystic kidney with hepatic cysts and complicated by cholangiocellular carcinoma is rare, but should be considered among the differential diagnosis for FUO, which itself is frequently encountered.