Open AccessRenal Sarcoidosis Monitored with Gallium Scintigraphy: Report of a Case
Author(s) -
Morimoto Takeshi,
Watanabe Koji,
Kobashi Ryotaro,
Kanaji Kenji,
Matsumura Tadashi,
Doi Toshio
Publication year - 2000
Publication title -
general medicine
Language(s) - English
Resource type - Journals
eISSN - 1883-6011
pISSN - 1346-0072
DOI - 10.14442/general2000.1.23
Subject(s) - medicine , sarcoidosis , scintigraphy , interstitial nephritis , renal biopsy , corticosteroid , biopsy , pathology , hypercalciuria , uveitis , radiology , kidney , urinary system , immunology
A 60‐year‐old male was diagnosed as having sarcoidosis four months previously because of bilateral hilar lymphadenopathy seen on a chest X‐ray, uveitis, and elevation of serum angiotensin converting enzyme. In summer, the patient suffered from hypercalcemia, hypercalciuria, and renal dysfunction. Renal biopsy showed interstitial nephritis with gallium scintigraphy demonstrating high uptake in the bilateral hilum, eyes, and kidneys. Corticosteroid treatment was effective in remarkably improving the renal disorder and radiographic abnormalities. The calcium metabolic abnormalities and the granulomatous interstitial nephritis showed a marked response to corticosteroid therapy, so that immediate administration of corticosteroid may be justified even in cases without histological evidences. Gallium scintigraphy is suggested to be useful in noninvasive examination in acute stage of sarcoidosis.