Open AccessCerebral Infarction in an Elderly Patient during Dabigatran Treatment
Author(s) -
Nishizaki Yuji,
Yamagami Shinichiro,
Sasano Hitoshi,
Sai Eiryu,
Takamura Kazuhisa,
Nakahara Toshiki,
Furukawa Yoshiaki,
Daida Hiroyuki
Publication year - 2015
Publication title -
general medicine
Language(s) - English
Resource type - Journals
eISSN - 1883-6011
pISSN - 1346-0072
DOI - 10.14442/general.16.41
Subject(s) - medicine , dabigatran , bradycardia , gastrointestinal bleeding , anesthesia , digitalis , atrial fibrillation , stroke (engine) , blood pressure , cerebral infarction , anemia , cardiology , warfarin , heart failure , heart rate , mechanical engineering , ischemia , engineering
A 91 year‐old male who was orally receiving dabigatran and digitalis for chronic arterial fibrillation was hospitalized for cerebral infarction (CI). The complications of anemia due to gastrointestinal bleeding and the development of renal failure were also found, which enhanced the effect of digitalis. This enhanced drug action induced bradycardia and hypotension. The hypotension was improved by implanting a temporary pacemaker, and the neurological abnormal findings also disappeared with the improved blood pressure. In many cases, dabigatran is efficient in preventing CI, but in our case it in fact triggered a CI hemodynamically due to bradycardia and hypotension with gastrointestinal bleeding.