Open AccessImprovement in Symptoms and QuantiFERON TB‐2G Test Results after Isoniazid Administration in a Patient with Normal Routine Tests Results
Author(s) -
Kawada Etsuo,
Sato Hiroko,
Kaneko Naoko,
Ohyama Yoshio,
Tamura Jun'ichi
Publication year - 2010
Publication title -
general medicine
Language(s) - English
Resource type - Journals
eISSN - 1883-6011
pISSN - 1346-0072
DOI - 10.14442/general.11.31
Subject(s) - medicine , isoniazid , quantiferon , tuberculosis , mycobacterium tuberculosis , latent tuberculosis , diagnostic test , tuberculosis diagnosis , pediatrics , pathology
Diagnosis is difficult in patients who complain of slight fever without objective abnormalities. It is not rare that patients without signs of typical Mycobacterium tuberculosis (TB) infection have a delayed TB diagnosis. It has been reported that the QuantiFERON TB‐2G test is useful for diagnosing latent TB infection. We report a patient who suffered from sweating, body weight loss, and a fever of less than 37. 5C without abnormalities in routine tests. Except for his complaints, only QuantiFERON TB‐2G testing suggested his illness, after which he was successfully treated with isoniazid administration. QuantiFERON TB‐2G testing might be useful to diagnose patients with slight fever when TB is suspected but a conventional workup is not diagnostic.