Open AccessIncidence of Pump Thrombosis in HeartMate II during Destination Therapy
Author(s) -
Rohan Samson,
Abhishek Jaiswal,
Frank W. Smart,
Thierry H. LeJemtel
Publication year - 2016
Publication title -
the vad journal
Language(s) - English
Resource type - Journals
ISSN - 2378-2706
DOI - 10.14434/vad.v2i0.27955
Subject(s) - medicine , thrombosis , incidence (geometry) , ventricular assist device , cardiology , destination therapy , surgery , heart failure , physics , optics
Pump thrombosis occurs during destination therapy (DT) with HeartMate II, a continuous blood flow left ventricular assist device (St Jude, Pleasanton, CA, USA). With adherence to stringent post-operative and long-term anticoagulation a low incidence of pump thrombosis was initially reported during DT. The increased PT incidence during DT that was reported in early 2013 was attributed to lenient anticoagulation. A wide range of pump thrombosis incidence during DT is being reported since the return to stringent post-operative and long-term anticoagulation. We searched PubMed from January 2008 to February 2016 for reports of pump thrombosis during mechanical circulatory support with HeartMate II and focus on the incidence rate of pump thrombosis from DT approval by the Food and Drug Administration to present. Pump thrombosis which may have been initially underestimated continues to complicate DT with HeartMate II despite stringent post-operative and long-term anticoagulation.