Open AccessMultistep organic synthesis leading to the formation of triazinothiazoloquinoxalines involving cost effective rea-gents
Author(s) -
Amar Prasad Yadav,
V. K. Pandey
Publication year - 2017
Publication title -
international journal of scientific world
Language(s) - English
Resource type - Journals
ISSN - 2307-9037
DOI - 10.14419/ijsw.v5i2.6154
Subject(s) - ammonium thiocyanate , oxalic acid , reagent , thiocyanate , chemistry , ammonium acetate , combinatorial chemistry , ammonium , reaction conditions , organic chemistry , catalysis , high performance liquid chromatography
A simple and efficient chemical method has been attempted for the synthesis of biologically and commercially important 2-aryl [-s-] triazino [1], [3], [5] thiazolo [6], [5-b] quinoxalin -4- thiones in moderate to excellent yields through cyclization reaction of o-phenylenediamino using readily available and fewer costly reagents viz. oxalic acid, PCl5thiourea, aromatic aldehydes and ammonium thiocyanate at an ambient temperature.