Pharmacological evaluation of oxazine sulfonamide derivatives for anti-inflammatory, analgesic and antipyretic activities | Zendy

Shailaja Ande | Zendy; Khadar Shaik | Zendy; Ravi Dharmoji | Zendy; Nisa Firdouse | Zendy; Anjum Mohd | Zendy; Sowmya Yelwarthi | Zendy

Open Access

Pharmacological evaluation of oxazine sulfonamide derivatives for anti-inflammatory, analgesic and antipyretic activities

Author(s) -

Shailaja Ande,

Khadar Shaik,

Ravi Dharmoji,

Nisa Firdouse,

Anjum Mohd,

Sowmya Yelwarthi

Publication year - 2016

Publication title -

international journal of pharmacology and toxicology

Language(s) - English

Resource type - Journals

ISSN - 2310-2985

DOI - 10.14419/ijpt.v4i2.6123

Subject(s) - analgesic , antipyretic , pharmacology , carrageenan , anti inflammatory , antifungal , antithrombotic , ibuprofen , sulfonamide , chemistry , medicine , organic chemistry , dermatology , cardiology

Oxazine heterocyclic compound containing one oxygen and one nitrogen atom. They possess different pharmacological activities like anticancer, anti-ulcer, antifungal, antithrombotic, antihypertensive, analgesic, anti-inflammatory etc. Oxazine Sulphonamide derivatives were investigated for anti-inflammatory, analgesic and anti-pyretic activities. It was evaluated for anti-inflammatory activity by carrageenan induced paw edema in rats using Plethysmometer and it also shows significant analgesic effect in male Albino mice. Antipyretic activity was also investigated.

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