Open AccessPharmacological evaluation of oxazine sulfonamide derivatives for anti-inflammatory, analgesic and antipyretic activities
Author(s) -
Shailaja Ande,
khadar Shaik,
Ravi Dharmoji,
Nisa Firdouse,
Anjum Mohd,
Sowmya Yelwarthi
Publication year - 2016
Publication title -
international journal of pharmacology and toxicology
Language(s) - English
Resource type - Journals
ISSN - 2310-2985
DOI - 10.14419/ijpt.v4i2.6123
Subject(s) - analgesic , antipyretic , pharmacology , carrageenan , anti inflammatory , antifungal , antithrombotic , ibuprofen , sulfonamide , chemistry , medicine , organic chemistry , dermatology , cardiology
Oxazine heterocyclic compound containing one oxygen and one nitrogen atom. They possess different pharmacological activities like anticancer, anti-ulcer, antifungal, antithrombotic, antihypertensive, analgesic, anti-inflammatory etc. Oxazine Sulphonamide derivatives were investigated for anti-inflammatory, analgesic and anti-pyretic activities. It was evaluated for anti-inflammatory activity by carrageenan induced paw edema in rats using Plethysmometer and it also shows significant analgesic effect in male Albino mice. Antipyretic activity was also investigated.