Open AccessSevere Ulcerative Colitis Flare Unmasking Factor VII Deficiency
Author(s) -
Paul Muńa Aguon,
Tyler Aasen,
Kaivan Salehpour,
Scott McShane
Publication year - 2018
Publication title -
international journal of medicine
Language(s) - English
Resource type - Journals
ISSN - 2309-1622
DOI - 10.14419/ijm.v6i1.8840
Subject(s) - ulcerative colitis , medicine , factor vii , gastroenterology , clotting factor , inflammatory bowel disease , flare , disease , immunology , coagulation , physics , astrophysics
We present a 22-year-old male with severe bleeding from Ulcerative Colitis. Workup revealed anemia and elevated prothrombin time, with subsequent mixing study and clotting factor levels revealing factor VII deficiency. Bleeding disorders such as Factor VII deficiency may exacerbate the degree of hemorrhage in inflammatory bowel disease flares, making prompt recognition of underlying coagulopathies crucial.