Open AccessHematological and immunological effects of gallium, indium, and arsenic in light emitting diodes manufacturing workers
Author(s) -
Ying-Yu Liao
Publication year - 2015
Publication title -
international journal of medicine
Language(s) - English
Resource type - Journals
ISSN - 2309-1622
DOI - 10.14419/ijm.v3i1.4642
Subject(s) - mean corpuscular volume , urine , gallium , arsenic , mean corpuscular hemoglobin concentration , indium , hemoglobin , white blood cell , medicine , immunology , mean corpuscular hemoglobin , chemistry , physiology , organic chemistry
Purpose: To determine whether hematological and immunological changes occur in manufacturing workers in association with gallium, indium, and arsenic biomarkers in light-emitting diodes.Methods: 91exposed light-emitting diodes, workers and 24 referents were monitored for whole blood and urine levels of gallium, indium, and arsenic. Venous blood was also collected for routine and immunological analyses.Results: The mean levels of blood in, urine Ga, urine as, and mean corpuscular hemoglobin concentration (MCHC) in the exposed workers were significantly than in referents. The values of mean corpuscular volume (MCV), white blood cell counts (WBCs), neutrophils, lymphocytes, interferon-γ (IFN-γ), and IgG in the exposed workers were lower than in referents. Combined exposure to Ga, In, and As showed a significant change in trends of decreased MCV, WBCs, neutrophils, lymphocytes, IFN,γ, and IgG value, after adjusting for appropriate confounders.Conclusion: These findings indicated that heavier exposed to Ga, In, and As may suppress hematological and immunological variables.