Open AccessVibrational biospectroscopic study and chemical structure analysis of unsaturated polyamides nanoparticles as anti–cancer polymeric nanomedicines using synchrotron radiation
Author(s) -
Alireza Heidari
Publication year - 2018
Publication title -
international journal of advanced chemistry
Language(s) - English
Resource type - Journals
ISSN - 2310-2977
DOI - 10.14419/ijac.v6i2.12528
Subject(s) - attenuated total reflection , fourier transform infrared spectroscopy , synchrotron radiation , raman spectroscopy , materials science , polyamide , synchrotron , infrared , infrared spectroscopy , chemical structure , spectroscopy , polymer , nanoparticle , analytical chemistry (journal) , chemistry , chemical engineering , polymer chemistry , optics , composite material , nanotechnology , organic chemistry , physics , quantum mechanics , engineering
Firstly, unsaturated polyamides nanoparticles were hardened by continuous synchrotron radiation and then, the induced changes in its chemical structure were studied by Attenuated Total Reflection–Fourier Transform Infrared (ATR–FTIR) spectroscopy. It was shown that applying synchrotron radiation for hardening not only leads to reduction of hardening time but also creates cross link in polymer by breaking Carbon–Carbon double bond, without any considerable change in its chemical structure. In addition, an unsaturated polyamide nanoparticle as anti–cancer polymeric nanomedicines is hardened by synchrotron radiation. Its chemical structure before and after hardening is studied using Raman and Attenuated Total Reflection–Fourier Transform Infrared (ATR–FTIR) spectroscopy. The results show that Raman spectroscopy is considerably better than Attenuated Total Reflection–Fourier Transform Infrared (ATR–FTIR) spectroscopy in detecting the changes happened in chemical structure.