Open AccessClinical manifestations of prolactin-secreting pituitary tumors in children and adolescents
Author(s) -
I.B. Zhurtova Zhurtova,
Н. А. Стребкова,
V А Peterkova,
А В Воронцов,
А. В. Ильин
Publication year - 2012
Publication title -
problemy èndokrinologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.124
H-Index - 5
eISSN - 2308-1430
pISSN - 0375-9660
DOI - 10.14341/probl20125848-13
Subject(s) - prolactin , medicine , incidence (geometry) , pituitary tumors , pituitary adenoma , pituitary neoplasm , prolactinoma , pituitary gland , pediatrics , adenoma , physiology , pathology , endocrinology , hormone , physics , optics
Scarce clinical manifestations of prolactin-secreting pituitary tumors in children and adolescents make it difficult to timely diagnosis. Girls have more prevalence of microprolactinomas, manifests as a rule, menstrual irregularities. In males, the greater incidence of macroadenomas results in the presence of neuroophthalmologic signs. The diagnosis of prolactinomas requires both radiographic evidence of pituitary adenoma and laboratory analysis of sustained hyperprolactinemia.