Open AccessThiazolidinediones: a long way to clinical practice
Author(s) -
А. А. Александров,
Svetlana Semenovna Kukharenko,
М. Н. Ядрихинская,
О. А. Шацкая,
Е Н Дроздова
Publication year - 2011
Publication title -
problemy èndokrinologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.124
H-Index - 5
eISSN - 2308-1430
pISSN - 0375-9660
DOI - 10.14341/probl201157657-63
Subject(s) - clinical practice , medicine , type 2 diabetes mellitus , coronary heart disease , diabetes mellitus , intensive care medicine , endocrinology , physical therapy
The clinical application of thiazolidinediones has an almost 12 year history. The correction of carbohydrate metabolism achieved by the treatment with hiazolidinediones is associated with the reduction of many risk factors of coronary heart disease and the improvement of prognosis for the patients presenting with type 2 diabetes mellitus. The possible mechanisms underlying complications encountered in the clinical practice in connection with the use of thiazolidinediones are discussed.