Brain GABA-receptor systems in functional thyroid disorders | Zendy

Flora Inoyatova | Zendy; A K Tonkikh | Zendy; G T Yakubova | Zendy

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Brain GABA-receptor systems in functional thyroid disorders

Author(s) -

Flora Inoyatova,

A K Tonkikh,

G T Yakubova

Publication year - 2009

Publication title -

problems of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.124

H-Index - 5

eISSN - 2308-1430

pISSN - 0375-9660

DOI - 10.14341/probl200955528-30

Subject(s) - neuroscience , thyroid , receptor , medicine , biology , endocrinology

This experimental study was designed to evaluate effects of hypo- and hyperthyroidism on the density of 3H-muscimol and 3H-diazepam-binding sites in synaptic membranes of the rat brain. It was shown that density of both 3H-muscimol and 3H-diazepam-binding sites increases in animals with hypothyroidism and decreases in hyperthyroidism. This difference may account for the predominance of general inhibitory reaction in animals with hypothyroidism and general excitation in hyperthyroid rats.

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