Open AccessNew evidence for the pathogenesis of obesity: adipokines are adipose tissue hormone
Author(s) -
А. В. Косыгина,
O. V. Vasyukova
Publication year - 2009
Publication title -
problemy èndokrinologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.124
H-Index - 5
eISSN - 2308-1430
pISSN - 0375-9660
DOI - 10.14341/probl200955144-50
Subject(s) - adipokine , adipose tissue , pathogenesis , medicine , hormone , obesity , endocrinology , leptin , bioinformatics , biology
In recent years, the independent role of adipose tissue in the pathogenesis of obesity and related complications has been actively discussed. Adipose tissue is also a key factor in the development and progression of insulin resistance. Among adipokines secreted by adipose tissue and influencing the development of insulin resistance and metabolic disorders, the most studied are leptin, adiponectin, resistin, visfatin. These adipokines are dedicated to this review.