
The functional state of the thyroid system in pregnant women, women in childbirth and puerperas in Belarus
Author(s) -
A. M. Iskritsky,
S. E. Sorokina
Publication year - 1997
Publication title -
problemy èndokrinologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.124
H-Index - 5
eISSN - 2308-1430
pISSN - 0375-9660
DOI - 10.14341/probl199743620-22
Subject(s) - triiodothyronine , pregnancy , thyroid , medicine , thyroid function , goiter , childbirth , gestation , thyroxine binding globulin , endocrinology , hormone , physiology , iodine , obstetrics , biology , chemistry , genetics , organic chemistry
The study was aimed at detecting the disorders and specific features in the function of the thyroid system in pregnant women, parturients, and puerperae in Byelorussia after the Chernobyl accident. Serum total thyroxin, total triiodothyronine, and thyroxin-binding globulin were radioimmunoassayed in 151 women. The concentrations of total thyroxin and total triiodothyronine were decreased during the second and at the beginning of the third gestation trimesters, these changes being most expressed in regions with radionuclide pollution, which are, in addition, intensive foci of endemic goiter. Insufficient intake of iodine under conditions of activated metabolism associated with pregnancy appears to be responsible for the functional changes in the thyroid system. Renewal of iodine prophylaxis is recommended for pregnant women living at territories contaminated with radionuclides.