Open AccessThe clinical practice guidelines for primary hyperparathyroidism, short version
Author(s) -
Natalia Mokrysheva,
Anna Eremkina,
Svetlana Mirnaya,
Julia Krupinova,
И А Воронкова,
I. V. Kim,
D. G. Beltsevich,
N S Kuznetzov,
Ekaterina Pigarova,
L Ya Rozhinskaya,
M. V. Degtyarev,
Lilit Egshatyan,
P A Rumiantsev,
Е. Н. Андреева,
M.B. Antsiferov Antsiferov,
Н. В. Маркина,
I. V. Kryukova,
Tatiana Karonova,
S. V. Lukyanov,
I V Sleptcov,
Н. Б. Чагай,
Г. А. Мельниченко,
И И Дедов
Publication year - 2021
Publication title -
problemy èndokrinologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.124
H-Index - 5
eISSN - 2308-1430
pISSN - 0375-9660
DOI - 10.14341/probl12801
Subject(s) - primary hyperparathyroidism , medicine , hyperparathyroidism , endocrine disease , incidence (geometry) , pediatrics , parathyroid hormone , endocrine system , disease , intensive care medicine , hormone , calcium , physics , optics
Primary hyperparathyroidism (PHPT) is an endocrine disorder of parathyroid glands characterized by excessive secretion of parathyroid hormone (PTH) with an upper normal or elevated blood calcium level. Classical PHPT refers to a symptomatic, multi-system disorder, wich can lead to a significant decrease in the quality of life, disability of patients, and even an increased risk of premature death. Hypercalcemia and the catabolic effect of PTH on various cells are considered as the main pathogenetic mechanisms of the PHPT associated complications. In the last two decades, there has been an increase in the incidence of PHPT, mainly due to the mild forms of the disease, primarily due to the routine calcium screening in North America, Western Europe and, Asia. High prevalence of the disease, as well as the variety of clinical manifestations, cause the attention of different specialists - physicians, rheumatologists, urologists, nephrologists, cardiologists and other doctors. This review cover the main issues of Russian guidelines for the management of PHPT, approved in 2020, including laboratory and instrumental methods, differential diagnosis, surgical and conservative approach, short-term and long-term follow-up. This guidelines also include the recommendations for special groups of patients with hereditary forms of PHPT, parathyroid carcinoma, PHPT during pregnancy.