Effect of I-131 incorporation on male rat reproductive system and the dose-dependent effect | Zendy

Л. В. Тарасенко | Zendy; S. V. Varga | Zendy; В. Н. Демченко | Zendy; Ye. V. Bolshova | Zendy; N. D. Nosenko | Zendy; P. V. Sinitsyn | Zendy; L. V. Chaikovskaya | Zendy; А. Г. Резников | Zendy

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Effect of I-131 incorporation on male rat reproductive system and the dose-dependent effect

Author(s) -

Л. В. Тарасенко,

S. V. Varga,

В. Н. Демченко,

Ye. V. Bolshova,

N. D. Nosenko,

P. V. Sinitsyn,

L. V. Chaikovskaya,

А. Г. Резников

Publication year - 1994

Publication title -

problems of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.124

H-Index - 5

eISSN - 2308-1430

pISSN - 0375-9660

DOI - 10.14341/probl12016

Subject(s) - reproductive system , medicine , endocrinology , testosterone (patch) , male reproductive system , adult male , biology , chemistry , andrology , sperm

Radioactive 131Iwas injected in single doses 9.25, 37, and 92.5 kBq to prepubertal (30-day-old) male rats. Iodine incorporation in doses 37 and 92.5 kBq resulted in some functional changes in the reproductive system of mature rats: blood testosterone level increased, its hypothalamic aromatization intensified, and biologically active LH level in the blood dropped. Incorporation of 9.25 kBq of 131-I had no effect on male reproductive system. A possibility of direct injury to rat testicles by 131I incorporation is suggested.

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