Open AccessEffect of I-131 incorporation on male rat reproductive system and the dose-dependent effect
Author(s) -
Л. В. Тарасенко,
S. V. Varga,
В. Н. Демченко,
Ye. V. Bolshova,
N. D. Nosenko,
P. V. Sinitsyn,
L. V. Chaikovskaya,
Alexander Reznikov
Publication year - 1994
Publication title -
problemy èndokrinologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.124
H-Index - 5
eISSN - 2308-1430
pISSN - 0375-9660
DOI - 10.14341/probl12016
Subject(s) - reproductive system , medicine , endocrinology , testosterone (patch) , male reproductive system , adult male , biology , chemistry , andrology , sperm
Radioactive 131Iwas injected in single doses 9.25, 37, and 92.5 kBq to prepubertal (30-day-old) male rats. Iodine incorporation in doses 37 and 92.5 kBq resulted in some functional changes in the reproductive system of mature rats: blood testosterone level increased, its hypothalamic aromatization intensified, and biologically active LH level in the blood dropped. Incorporation of 9.25 kBq of 131-I had no effect on male reproductive system. A possibility of direct injury to rat testicles by 131I incorporation is suggested.