Morphofunctional analysis of the status of some endocrine glands in candidiasis

Morphometric analysis of the thyroid, parathyroid glands and adrenal cortex was carried out in mice with candidiasis. A grave systemic form of candidiasis, that eventuated in the death of the animals, was associated with a reduction of the functional activities of the thyroid and parathyroid glands and a drastic activation of the adrenal cortex. A benign course of the infection was parallelled by a moderate inhibition of the thyroid activity, followed by its activation and normalization. Changes of the parathyroid activity were negligible in such a case, and the adrenocortical activity is moderately growing at the peak of the infection and normalizes later.