Open AccessEffect of hyperbaric oxygenation on microcirculation, oxygen budget, and acid base balance of patients with diabetic angiopathies of the lower limbs
Author(s) -
M G Gonchar,
Zh M Vavrik,
Ye. I. Deltsova,
R. G. Zelenetsky
Publication year - 1993
Publication title -
problemy èndokrinologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.124
H-Index - 5
eISSN - 2308-1430
pISSN - 0375-9660
DOI - 10.14341/probl11943
Subject(s) - microcirculation , medicine , oxygenation , diabetes mellitus , cardiology , metabolic acidosis , acidosis , hypoxia (environmental) , oxygen saturation , anesthesia , oxygen , endocrinology , chemistry , organic chemistry
These effects were studied in 52 patients with degrees III-IV diabetic angiopathies of the lower limbs. Microcirculation parameters were found changed in this patient population, this leading to disorders of the oxygen budget and development of metabolic acidosis. Development of destructive changes in the limb evidences failure of the compensatory adaptive mechanisms of microcirculation. Addition of hyperbaric oxygenation to multiple-modality treatment of patients with diabetic angiopathies was conducive to improvement of the blood rheology, of tissue saturation with oxygen, and to essential reduction of metabolic acidosis. The detected microcirculation disorders necessitate addition to the therapeutic complex of the drugs improving the biophysical characteristics of the blood.