Open AccessThe use of the drug Wessel Duet F in the complex treatment of lesions of the lower extremities in patients with type II diabetes
Author(s) -
Alla Y. Tokmakova,
T. M. Milenkaya,
Л Д Чиркова,
М И Арбузова,
М. Б. Анциферов
Publication year - 1999
Publication title -
problemy èndokrinologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.124
H-Index - 5
eISSN - 2308-1430
pISSN - 0375-9660
DOI - 10.14341/probl11760
Subject(s) - medicine , type 2 diabetes , diabetes mellitus , peripheral , amputation , blood flow , cardiology , hemodynamics , arterial disease , arteriosclerosis , vascular disease , surgery , endocrinology
A comprehensive approach to treatment of ischemic involvement of the lower limbs in patients with type 2 diabetes is proposed. Diabetics often develop obliterating atherosclerosis of the lower limb arteries; the risk of amputation of feet and shins, involving invalidism and death, is rather high. The authors assessed the effect of Vessel Due F (Alfa Wasserman, Italy) on lipid metabolism, blood rheology, and peripheral hemodynamics in 30 patients with type 2 diabetes complicated by the ischemic form of diabetic foot. The course of therapy lasted for 12 weeks. Lipid metabolism notably improved (total cholesterol level decreased), normocoagulation and normalization of peripheral arterial blood flow were attained in the majority of patients, as shown by dopplerography. Therefore, the drug is effective in the treatment of ischemic form of the lower limb involvement in patients with type 2 diabetes.