Open AccessEFFECT OF A 5-YEAR ALFACALCIDOL TREATMENT IN COMBINATION WITH CALCIUM CARBONATE ON BONE MINERAL DENSITY IN THE PRIMARY FORMS OF SYSTEMIC OSTEOPOROSIS IN MEN
Author(s) -
С. С. Родионова,
У Р Хакимов
Publication year - 2016
Publication title -
osteoporoz i osteopatii
Language(s) - English
Resource type - Journals
eISSN - 2311-0716
pISSN - 2072-2680
DOI - 10.14341/osteo2016122-27
Subject(s) - alfacalcidol , medicine , osteoporosis , bone mineral , calcium , urine , calcium carbonate , urology , endocrinology , chemistry , organic chemistry
The article presents the results of 5-year treatment with a combination of alfacalcidol and calcium carbonate in 47 men with primary forms of systemic osteoporosis. The obtained results show the effectiveness of this treatment in patients with low and normal turnover forms of osteoporosis. Significant increase of BMD at L1-L4 was observed after the first year of treatment, at the Neck region - after 3-rd year of treatment. Comparison of the magnitude of the annual increase of BMD has shown that the effectiveness of the treatment increases with its duration. The possibility of hypercalcemia was excluded by monitoring of calcium levels in blood and urine at intervals of 3-6 months throughout the treatment period.