Open AccessCLINICAL PREDICTORS OF LOW BONE MINERAL DENSITY IN CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITIS
Author(s) -
М. М. Костик,
V I Larionova,
L A Scheplyagina
Publication year - 2014
Publication title -
osteoporoz i osteopatii
Language(s) - English
Resource type - Journals
eISSN - 2311-0716
pISSN - 2072-2680
DOI - 10.14341/osteo2014211-15
Subject(s) - medicine , juvenile , arthritis , densitometry , bone mineral , juvenile rheumatoid arthritis , gastroenterology , osteoporosis , genetics , biology
The aim of this study was to assess the role of simple clinical and laboratorial markers for prediction of low bone mineral density (LBMD 5.0, DAS > 2.9, DAS28 > 4.2, JADAS 10 > 15.6, JADAS 27 > 15.1, CDAI > 18.1, Steinbrocker's functional class > 2, systemic arthritis, corticosteroid treatment, arthritis duration > 4.5 years, number of active joints > 5, number of painful joints > 9, morning stiffness > 90 minutes, parental overall JIA activity (VAS) > 5.8, ESR > 16 mm/h, CRP > 22.6 mg/l were associated with increased risk of LBMD in JIA children. Among metabolic markers Ca total 1.59 mmol/l also increased the possibility of LBMD. Our data can help to identify the JIA patients at risk for LBMD and to suggest the indications for densitometry evaluation of JIA children.