Open AccessAdipokines: mechanisms of metabolic and behavioral disorders
Author(s) -
Yassine Chahirou,
Abdelhalem Mesfioui,
Ali Ouichou,
Aboubaker El Hessni
Publication year - 2018
Publication title -
ožirenie i metabolizm
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.154
H-Index - 5
eISSN - 2306-5524
pISSN - 2071-8713
DOI - 10.14341/omet9430
Subject(s) - adipokine , insulin resistance , dyslipidemia , metabolic syndrome , adipose tissue , oxidative stress , endocrinology , lipogenesis , medicine , endocrine system , bioinformatics , diabetes mellitus , biology , hormone
Current studies show that metabolic and behavioral disorders represent severe health problems. Several questions arise about the molecular relationship of metabolic and behavioral disorders. This review will discuss the relationship of lipid metabolism and fructose consumption accompanied by an increase in weight as well as associated disorders: hypertension, insulin-resistance, oxidative stress and depression. Adipose tissue is considered as an endocrine tissue with intense secretory activities (metabolic and inflammatory). These adipokines are responsible for an alteration of several physiological functions. In this review we will try to understand how lipogenesis that causes dyslipidemia can influence insulin resistance, hypertension, oxidative stress, depression and the relationship between these various disorders.