Open AccessThe effect of type 2 diabetes and its drug therapy on bone quality.
Author(s) -
T O Yalochkina,
Ekaterina Pigarova
Publication year - 2015
Publication title -
ožirenie i metabolizm
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.154
H-Index - 5
eISSN - 2306-5524
pISSN - 2071-8713
DOI - 10.14341/omet2015341-45
Subject(s) - medicine , type 2 diabetes , diabetes mellitus , fragility , drug , disease , mechanism (biology) , endocrinology , pharmacology , chemistry , philosophy , epistemology
Individuals with type 2 diabetes have increased risk of fragility fractures. It’s not completely clear by which mechanism type 2 diabetes increases skeletal fragility. A combination of factors, including an increased risk of falling (contributed by complications of the disease) and impaired bone quality apparently leads to a greater fracture risk. Some cl asses of drug therapy for type 2 diabetes may also increase fracture risk by their own mechanism of action.