Open AccessMetabolic disorders in medulloblastoma and acute lymphoblastic leukemia survivors
Author(s) -
Tat'yana Yur'evna Tseloval'nikova,
Целовальникова Татьяна Юрьевна,
М Г Павлова,
Павлова Мария Геннадиевна,
Alexey Zilov,
Зилов Алексей Вадимович,
Nadezhda Mazerkina,
Мазеркина Надежда Александровна,
Olga Zheludkova,
Желудкова Ольга Григорьевна,
Ирина Алексеевна Арефьева,
Арефьева Ирина Алексеевна,
О. А. Медведева,
Медведева Ольга Александровна
Publication year - 2015
Publication title -
ožirenie i metabolizm
Language(s) - English
Resource type - Journals
eISSN - 2306-5524
pISSN - 2071-8713
DOI - 10.14341/omet201533
Subject(s) - medulloblastoma , medicine , childhood cancer , lymphoblastic leukemia , cancer , leukemia , pediatrics , intensive care medicine , acute leukemia , oncology , cancer research
The childhood cancer morbidity has been steadily increasing over the last few decades. However, the recent more effective complex treatment approaches have led to a dramatic improvements in the survival rate in childhood cancers. Currently many childhood cancer survivors require a life-long follow-up. Therefore, today doctors of various specialties are faced with different long-term consequences after the complex treatment for cancer. Among the various complications metabolic disorders should be eparately identified as risk factors for cardiovascular diseases, which are the most frequent causes of death. This article describes the current understanding of the various metabolic changes in the patients after treatment for medulloblastoma and acute lymphoblastic leukemia in childhood, the mechanisms of their development and treatment issues.