Open AccessEffects of bariatric surgery on the level of hormones that regulate body weight. What is the basis of success?
Author(s) -
Alina Yur'evna Babenko,
Aleksandr Evgen'evich Neymark,
К. А. Анисимова,
Eleikolaevikolaevna Grineva Eleikolaevna
Publication year - 2014
Publication title -
ožirenie i metabolizm
Language(s) - English
Resource type - Journals
eISSN - 2306-5524
pISSN - 2071-8713
DOI - 10.14341/omet201443-11
Subject(s) - adipokine , obesity , medicine , incidence (geometry) , appetite , type 2 diabetes , hormone , surgery , intensive care medicine , diabetes mellitus , leptin , endocrinology , physics , optics
The growth of obesity and type 2 diabetes incidence has made bariatric surgery a widespread method of treatment. The effectiveness of bariatricoperations in the treatment of obesity and related metabolic diseases is thoroughly highlighted in medical literature. However, the resultsof surgery do not always correlate with type of operation. As before, the mechanisms have not been fully studied of how the bariatric surgeryinfluence on insulinresistance, entero-insulin axes, adipokines. Understanding such mechanisms will allow us to determine more precisely theindications relating to surgical treatment, and enhance the effectiveness of surgery in specific patient. The review is focusing on the influence ofvarious types of bariatric surgery on the level of adipokines and incretines that participate in regulation of appetite and of fat and carbohydratemetabolism. The article elaborates modern concepts related to the impact of bariatric operations on metabolic disorders in obesity.