Open AccessNephrolithiasis in primary hyperparathyroidism: a contemporary look
Author(s) -
Перетокина Елена Викторовна,
Mokrysheva Natalya Georgievna
Publication year - 2014
Publication title -
ožirenie i metabolizm
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.154
H-Index - 5
eISSN - 2306-5524
pISSN - 2071-8713
DOI - 10.14341/omet201433-8
Subject(s) - nephrocalcinosis , primary hyperparathyroidism , medicine , asymptomatic , disease , hyperparathyroidism , kidney
Primary hyperparathyroidism (PHPT) has attracted a growing attention of medical doctors of different specialties in the last few years. The ability to predict the risk of the development of visceral manifestations (nephrolithiasis, nephrocalcinosis, cardiovascular disease, peptic ulcer disease) in the mild asymptomatic PHPT can define indications for conservative treatment of such patients because of the high prevalence of the mild form of the disease. Nephrolithiasis is one of the most common manifestations of the PHPT and is one of the indications for surgery. Mechanisms of nephrolithiasis and nephrocalcinosis in PHPT remain unclear and many investigations are devoted to studying the possible predictors of its development. In this paper we review the current knowledge of nephrolithiasis, clinical features and risk factors of its development in patients with PHPT.