Open AccessThe role of gut microbiota in metabolic regulation
Author(s) -
Е. Н. Кравчук,
A. E. Neimark,
Elena Grineva,
M. M. Galagudza
Publication year - 2016
Publication title -
saharnyj diabet
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.155
H-Index - 12
eISSN - 2072-0378
pISSN - 2072-0351
DOI - 10.14341/dm7704
Subject(s) - obesity , disease , gut flora , metabolic syndrome , type 2 diabetes , pathological , diabetes mellitus , bioinformatics , biology , metabolic disease , medicine , intensive care medicine , immunology , endocrinology
Obesity and metabolic syndrome are among the major problems of modern society. The increase in obesity is associated with a corresponding increase in type 2 diabetes, cardiovascular disease and cancer. A huge amount of scientific research has been devoted to the development of methods to reduce obesity and its complications. In recent years, attention has shifted towards studying the intestinal microbiota not only as a possible component of the pathological process but also as a target of therapeutic intervention. Recent evidence, primarily from investigations in animal models, suggests that the intestinal microbiota affects nutrient acquisition and energy regulation. This review will discuss the role of the intestinal microbiota in metabolic processes as well as the latest developments on the improvement of disturbances specific to obesity and metabolic syndrome.