Relationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes | Zendy

Д. Н. Лаптев | Zendy

Open Access

Relationship of hypoglycemia and glucose variability with autonomic dysfunction in children and adolescents with type 1 diabetes

Author(s) -

Д. Н. Лаптев

Publication year - 2014

Publication title -

diabetes mellitus

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.155

H-Index - 12

eISSN - 2072-0378

pISSN - 2072-0351

DOI - 10.14341/dm2014487-92

Subject(s) - medicine , heart rate variability , hypoglycemia , type 1 diabetes , autonomic neuropathy , diabetes mellitus , continuous glucose monitoring , cardiology , qt interval , autonomic nervous system , heart rate , endocrinology , blood pressure , biology , cell culture , genetics , neuroblastoma

Aim. Glucose variability (GV) and hypoglycaemia frequency and duration, depending on cardiovascular autonomic dysfunction, in children and adolescents with type 1 diabetes mellitus (T1DM) were evaluated. Materials and methods. One hundred and thirty T1DM patients, aged 6?18 years, were included in this study. The study included 3 tests:. continuous glucose monitoring (CGM) with GV evaluation, frequency and duration of hypoglycaemia;24-h ECG monitoring with automatic calculation of QTc interval and heart rate variability (HRV) parameters;cardiovascular autonomic tests.Results. The estimated prevalence of cardiovascular autonomic neuropathy (CAN) was 19.2%. CAN positive (CAN+) patients had lower values from cardiovascular autonomic tests and HRV and longer QTc intervals compared with CAN negative (CAN-) patients (p

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research