Open AccessGenetic framework of type 2 diabetes mellitus
Author(s) -
Ирина Аркадьевна Бондарь,
Бондарь Ирина Аркадьевна,
Olesya Yur'evna Shabel'nikova,
Шабельникова Олеся Юрьевна
Publication year - 2013
Publication title -
saharnyj diabet
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.155
H-Index - 12
eISSN - 2072-0378
pISSN - 2072-0351
DOI - 10.14341/dm2013411-16
Subject(s) - type 2 diabetes mellitus , medicine , insulin resistance , pathogenesis , adipogenesis , diabetes mellitus , endocrinology , insulin , type 2 diabetes , secretion , obesity , gene , bioinformatics , biology , genetics , adipose tissue
More than 100 genes associated with the risk of type 2 diabetes mellitus (T2DM) are now established. Most of them affect insulin secretion, adipogenesis and insulin resistance, but the exact molecular mechanisms determining their involvement in the pathogenesis of T2DM are not understood completely.