Open AccessArterial diseases of lower extremities in diabetic patients: current state and prospects of therapy
Author(s) -
Gagik R. Galstyan,
Галстян Гагик Радикович,
Alla Yur'evna Tokmakova,
Токмакова Алла Юрьевна,
О. Н. Бондаренко,
Бондаренко Ольга Николаевна,
Ivan Sitkin,
Ситкин Иван Иванович,
Kira Yur'evna Pryakhina,
Пряхина Кира Юрьевна,
Valeriy Afanas'evich Mitish,
Митиш Валерий Афанасьевич,
Lyubov' Petrovna Doronina,
Доронина Любовь Петровна
Publication year - 2011
Publication title -
saharnyj diabet
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.155
H-Index - 12
eISSN - 2072-0378
pISSN - 2072-0351
DOI - 10.14341/2072-0351-6253
Subject(s) - medicine , diabetic foot , asymptomatic , ischemia , diabetes mellitus , amputation , critical limb ischemia , surgery , peripheral , arterial disease , artery , cardiology , vascular disease , endocrinology
Peripheral artery diseases (PAD) are most serious diabetic complications responsible for the high risk of amputation of lower extremities. The occurrenceof PAD in diabetic patients is much higher than in subjects with undisturbed carbohydrate metabolism. PAD in diabetic patients is frequentlyan asymptomatic condition affecting distal portions of arterial segments and associated with pronounced mediacalcinosis. Standard diagnostic proceduresfor the screening of arterial lesions must be supplemented by non-invasive visualization and measurement of transcutaneous oxygen tensionin patients at risk of PAD and persisting foot ulcers. Of special importance is early diagnosis of critical limb ischemia and prevention of foot lesions.Combined treatment of diabetic foot syndrome in patients with critical limb ischemia includes normalization of foot circulation, surgical interventionand conservative therapy of the wound, monitoring concomitant micro- and macrovascular diabetic complications?