The results of open observational trial DIAMOND | Zendy

М. В. Шестакова | Zendy; Шестакова Марина Владимировна | Zendy; Olga Konstantinovna Vikulova | Zendy; Викулова Ольга Константиновна | Zendy

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The results of open observational trial DIAMOND

Author(s) -

М. В. Шестакова,

Шестакова Марина Владимировна,

Olga Konstantinovna Vikulova,

Викулова Ольга Константиновна

Publication year - 2011

Publication title -

diabetes mellitus

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.155

H-Index - 12

eISSN - 2072-0378

pISSN - 2072-0351

DOI - 10.14341/2072-0351-6232

Subject(s) - medicine , gliclazide , observational study , diabetes mellitus , randomized controlled trial , surgery , endocrinology

Aim. DIAMOND (DIAMicrON in Daily practice) is an open non-randomized observational trial aimed to estimate the efficacy and safety of gliclazide(Diamicron MB) in routine clinical practice. Materials and methods. 394 patients with poor control of type 2 diabetes mellitus (T2 DM), previously treated with diet or one of oral antidiabeticdrug (OAD), were switched to Diamicron MB. Previous therapy was left unchanged, except for a sulfonylurea or glinide that were canceled. Results. After 6 months of Diamicron MB therapy (30% monotherapy, 70% combined therapy) target HbA1c

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